Thus a key medicine was discovered

Pain is a necessary evil that warns us of imminent risks or ongoing damage. Is A defense mechanism that causes us to remove the hand of a burning surface or to avoid the blows.

Although millions of people live daily with pain, The analgesics available for decades are those that are usually known.

There are records in clay tables of four thousand years old showing recipes to combat pain: in the face of moderate pain, the sauce bark (similar to aspirin) was used; and before a very intense one, the poppy (opium).

In the 18th century, aspirin appears (1897), Paracetamol or acetaminophen (1878) and in the twentieth century the Dipirone (1922) and closer in time the ibuprofen (1962). If the pain is very intense and unbearable, the morphine is used (1920).

Although millions of people live with pain daily, the proposals for the use of analgesics had been offering the same alternatives for many years.

In January 2025, a new type of medication approved by the US FDA appears.which can become a very important and very novel tool in the fight against pain.

This is sumetrigin, which could change the prototype of pain managementproviding both patients and doctors for a totally different therapeutic option. And for two reasons:

1) for exercising its action on the electrical signals that run through the body.

2) For eliminating pain signals before they reach the brain. This is important since it prevents the patient from running the risk of entering an addictive, frequent process in whom he uses opioids.

For some researchers, a new era would be starting. The discovery of this analgesic had its origin -after many years of research – When studying a Pakistani family who could walk on the embers without feeling pain. That was the starting point that led to this remarkable medical advance so significant and impose the first analgesic of a new class in more than two decades.

The usual thing is that The pain begins in a certain part of the organism And that by specific nerve fibers the signal reaches the brain, registering its perception and is precisely in this organ where analgesics take their effect, especially the most powerful.

The novelty of sumetrigin is that Block the pain signal in the place where it originates Instead of doing so in brain receptors, such as opioids.

This eliminates the risk of dependence and addiction That has the consumption of the latter, particularly when the pain is very intense and prolonged over time.

“The sacred chalice of pain research was to find the molecules in our peripheral nerves and that we could block these signals. When focusing on the point of pain emission instead of the place of reception, many inconveniences and side effects are avoided. So It really is a great step forward”, Says Stephen Waxman, from Yale University (USA), who years ago studies the mechanisms used by the body to express pain.

This medicine It is not yet available in our country.